产品货号:
Z26127
中文名称:
SELPLG抗体
英文名称:
Anti-SELPLG Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-SELPLG Antibody |
指标别名 | CD162;CLA;PSGL 1;PSGL1;selectin P ligand;SELPLG |
克隆性 | Polyclonal |
检验物种 | mouse,rat |
应用范围 | WB,IHC,FCM,ELISA |
基因名称 | Selplg |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived mouse PSGL-1/Selplg recombinant protein (Position:L18-P397). |
实际分子量 | 110~120KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Selectin P ligand,also known as SELPLG or CD162 (cluster of differentiation 162),is a human gene.It is mapped to 5 F;5 55.59 cM.This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-,E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes.As such,this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins.This protein requires two post-translational modifications,tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans,for its high-affinity binding activity.Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.Alternate splicing results in multiple transcript variants. |
Uniprot ID | Q62170 |
基因名全称 | selectin,platelet (p-selectin) ligand |
蛋白名全称 | P-selectin glycoprotein ligand 1 |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunohistochemistry(Paraffin-embedded Section) 1:50~400 (ELISA): 1:100~1000 Flow Cytometry (FCM) 1~3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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